Clinical characteristics, treatment, and outcomes of fungal keratitis/endophthalmitis caused by Purpureocillium lilacinum. (PubMed, Front Cell Infect Microbiol) - Jun 18, 2026 - "Antifungal susceptibility testing showed high minimum inhibitory concentrations (MICs) to amphotericin B, 5-flucytosine and fluconazole; and high minimum effective concentrations (MECs) to micafungin and caspofungin, but low MICs to triazoles (voriconazole, isavuconazole, posaconazole, itraconazole)...lilacinum is an emerging fungal pathogen that exhibits intrinsic resistance to polyene antifungal agents (amphotericin B, natamycin), while being susceptible to triazole drugs...For progressive lesions, therapeutic keratoplasty may be required. This pathogen can pose a severe threat to visual acuity, highlighting the necessity of timely intervention."
Journal • Retrospective data • Conjunctivitis • Infectious Disease • Keratitis • Ocular Infections • Ocular Inflammation • Ophthalmology • Transplantation
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Hui Huang; Kaining Long; Li Jiang; Liuyang Hu; Qi Chen; Qianqian Lan; Xingchun Chen
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