INVASIVE ASPERGILLUS ORYZAE INFECTION FOLLOWING MULTIPLE NEUROSURGICAL INTERVENTIONS IN A TODDLER WITH CHIARI MALFORMATION TYPE I AND SYRINGOMYELIA. (ESPID 2026) - May 28, 2026 - Abstract #EPV-0056; Pres time: Jun 1, 2026; 07:00 AM - 07:00 PM; Location: E-Poster Area; "Liposomal amphotericin B (L-AMB) was started for six weeks, combining surgical site toilette and replacement of lumbar ventricular drain...Intravenous voriconazole and L- AMB were started, later shifted to isavuconazole (ISA) plus L-AMB due to intramedullary progression...This case highlights the value of mNGS as advanced complementary diagnostic approach. The eradication remains challenging due to the lesion's localization within a sanctuary site and structural features, specifically, the presence of a surrounding fibrotic ring that limits drugs penetration."
Infectious Disease
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Romani L. 1; Pagano F. 2; Cursi L. 1; Colagrossi L. 3; Scutari R. 3; Chiurchiù S. 1; Carboni A. 4; Bruzzese E. 5; Bernardi S. 1; Perno C.F. 3; Andrea L.V. 5; Guarino A. 5; Lancella L. 1
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