DISSEMINATED MUCORMYCOSIS: A DIAGNOSTIC AND THERAPEUTIC CHALLENGE (ESPID 2026) - May 28, 2026 - Abstract #EPV-0066; Pres time: Jun 1, 2026; 07:00 AM - 07:00 PM; Location: E-Poster Area; "During reinduction (6thcycle), he was admitted with febrile neutropenia and abdominal pain and empirically started on cefepime, escalated to meropenem, teicoplanin, and oral vancomycin following clinical deterioration and clostridial toxin detection...Persistent fever led to initiation of liposomal amphotericin-B(5mg/kg/day)...Deterioration requiring invasive ventilation, prompted addition of amikacin and isavuconazole, and CT-scan evinced lung extension...Two attempts to discontinue amphotericin due to renal toxicity (posaconazole or isavuconazole monotherapy) failed, as IFD progressed...Learning Points/Discussion Ultimately,3.5 years after, amphotericin was successfully withdrawn, and fosmanogepix combined with isavuconazole led to improvement of hepatic lesions in 3months (fig.1). Sustained oral therapy allowed school attendance and preserved quality-of-life."
Infectious Disease
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Gutiérrez Gutiérrez M. 1; Rincón López E. 2; Lancharro Zapata Á. 3; Guzman A.J. 4; García Morín M. 1; Angulo Chacón A.M. 5; Guinea Ortega J.V. 6; Cela De Julián E. 1; Navarro Gómez M.L. 2
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