A novel GWT1 A397T substitution combined with TAC1B F214I reduces manogepix susceptibility and fosmanogepix efficacy in Candida auris.

fosmanogepix (APX001) - Basilea

http://www.ncbi.nlm.nih.gov/pubmed/42678188

Hiroshi Mukae; Katsunori Yanagihara; Kazuhiro Tsukamoto; Koichi Izumikawa; Koichi Makimura; Mizuki Ishimine; Nana Nakada; Naoki Iwanaga; Natsume Kitahori; Taiga Miyazaki; Takahiro Takazono; Tatsuro Hirayama; Yuya Ito

Sep 2, 2026