Rezzayo (rezafungin for injection) - Mundipharma, Melinta Therap, Merck (MSD)
Olorofim (orotomide) - Shionogi
Cresemba (isavuconazonium sulfate) - Astellas, Basilea
fosmanogepix (APX001) - Basilea
Molecular Mechanisms, Diagnosis, and Therapeutic Strategies of Antifungal Resistance in Filamentous Fungi. (PubMed, J Fungi (Basel)) - Aug 27, 2026 - "Precision dosing guided by therapeutic drug monitoring, combination therapy, and the introduction of novel agents (including isavuconazole, rezafungin, fosmanogepix, and olorofim) are progressively improving clinical outcomes. Looking ahead, global surveillance and multisectoral collaboration are essential to deepen our understanding of resistance evolution, accelerate the clinical translation of novel diagnostic and therapeutic tools, and curb the global spread of resistance." 
Journal • Review
http://www.ncbi.nlm.nih.gov/pubmed/42646092
 
Lei Liu; Lipeng Zhang; Meng Zhao; Ruijie Li; Yajing Yin; Yueru Zhao
 
Aug 27, 2026
 
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