Dual Invasive Fungal Infections After Kidney Transplantation: A Case Report. (PubMed, J Fungi (Basel)) - Aug 27, 2026 - "We report a case of a 52-year-old woman who underwent deceased donor kidney transplantation complicated by probable donor-derived Candida albicans candidemia with native aortic valve endocarditis, managed medically with prolonged echinocandin therapy followed by suppressive fluconazole...Initial treatment with liposomal amphotericin B was limited by nephrotoxicity, prompting transition to isavuconazole for long-term management...This case illustrates the complex interplay between donor-derived infection, antifungal exposure, and immunosuppression in transplant recipients. It highlights the potential contribution of antifungal selective pressure to breakthrough mold infections and underscores the importance of early recognition, aggressive multidisciplinary management, and individualized antifungal strategies in this high-risk population."
Journal • Cardiovascular • Infectious Disease • Solid Organ Transplantation • Transplantation
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Ahmed Bishara; John Johnson; Laila Alshafai; Layan Akkielah; Leigh J Sowerby; Matthew A Weir; Michael Chiu; Michael Silverman; Mohammad Reza Rahimi Shahmirzadi
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