Population pharmacokinetics, target attainment and individualized dosing of isavuconazole in critically ill adults receiving extracorporeal membrane oxygenation. (PubMed, JAC Antimicrob Resist) - Aug 27, 2026 - "ECMO did not alter isavuconazole population clearance, so routine dose escalation is not warranted. Wide between-patient variability precludes any fixed regimen and favours therapeutic drug monitoring-guided individualized dosing."
Journal • PK/PD data • Acute Respiratory Distress Syndrome • Pulmonary Disease • Respiratory Diseases
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Christina Geiger; Lisa Kriegl; Philipp Eller; Robert Krause; Stefan Hatzl
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