Mutations in MRR1 that confer fluconazole resistance in C. parapsilosis and C. albicans confer cross-resistance to manogepix.

fluconazole oral - Generic mfg.

fosmanogepix (APX001) - Basilea

http://www.ncbi.nlm.nih.gov/pubmed/42551824

Hoja P Patterson; Joachim Morschhäuser; Katherine S Barker; Nathan P Wiederhold; P David Rogers

Aug 5, 2026