A Retrospective Study Comparing the Severe Cutaneous Adverse Reactions in Patients Receiving Triazole Antifungal Therapy and Literature Analysis. (PubMed, Med Mycol) - Aug 18, 2026 - "Fluconazole showed the strongest and most consistent statistical association across all four algorithms (ROR = 5.2), followed by itraconazole. Voriconazole yielded mixed signals (positive by ROR and BCPNN only), while Posaconazole and Isavuconazole exhibited no significant SCAR signals...This study identified significant variability of SCARs signals among triazole antifungals. These findings support early risk recognition and informed antifungal selection in clinical practice."
Journal • Retrospective data • Steven-Johnson Syndrome
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Cheng-Tao Jin; Ping Chen; Qian-Qian Jiang; Wei Jiang
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