SKIN-LIVER CROSSTALK ACCELERATES STEATOSIS AND INFLAMMATION IN METABOLIC DYSFUNCTION-ASSOCIATED STEATOTIC LIVER DISEASE (UEGW 2026) - Oct 23, 2026 - Abstract #DP140; Pres time: Oct 18, 2026; 09:00 AM - 06:00 PM; Location: Hall 7 Poster Area; "Subsequently, psoriasis-like dermatitis was induced by repeated topical application of imiquimod (IMQ)... Since IL-17A has been shown to be a driver cytokine in MASLD progression and increased hepatic lipid uptake leads to steatosis accumulation, these could represent mechanistic underpinnings of the clinically observed comorbidity of psoriasis and MASLD. Understanding the intricate relationships between these conditions is crucial for developing effective therapeutic and preventive approaches and improving overall patient outcomes."
Dermatitis • Fibrosis • Hepatology • Immunology • Inflammation • Liver Cancer • Liver Cirrhosis • Metabolic Disorders • Metabolic Dysfunction-Associated Steatohepatitis • Metabolic Dysfunction-Associated Steatotic Liver Disease • Psoriasis • Solid Tumor • CD36 • IL17A • SCARB1
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T. Bieler 1; K. Kommoss 2,1; S. Gallage 1,3; S.M. Kissmer 4; F. Han 3,1; S. Kam 3,1; P. Ramadori 1; A. Kadianaki 1,3; P. Shen 1; C. Trautwein 5; S. Karbach 6,7; A. Waisman 8; M.F. Heikenwälder 3,1
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