Formulation and Box-Behnken optimization of roflumilast loaded ultradeformable nanotransethosomal gel: physicochemical characterization, stability, dermal permeation, and antipsoriatic efficacy in an imiquimod-induced psoriasis model.

Zyclara (imiquimod) - Mochida, Viatris, Bausch Health

roflumilast - Generic mfg.

pimecrolimus topical - Generic mfg.

http://www.ncbi.nlm.nih.gov/pubmed/42733014

Achal Andhale; Rajashree Ghogare; Someshwar Mankar; Suhas Siddheshwar; Vaibhav Andhale

Sep 14, 2026