AUM-302, a novel triple PIM/PI3K/mTOR inhibitor, synergizes with RAS inhibition and impedes the growth of pancreatic ductal adenocarcinoma spheroids and organoids.

AUM302 - AUM Biosci

nuvisertib (TP-3654) - Sumitomo Pharma

daraxonrasib (RMC-6236) - Revolution Medicines

dactolisib (RTB101) - Adicet Bio

pictilisib (GDC-0941) - Roche

http://www.ncbi.nlm.nih.gov/pubmed/41756246

Agnieszka B Bialkowska; Amber N Habowski; Antonio T Baines; Catalina Vera; David A Tuveson; Emma Wen; Fatim Kouassi; Joseph F LaComb; Neecki Zand; Sahaana Kesavan

Feb 27, 2026