Subcutaneous Injection Of Botulinum Toxin For Brachioradial Pruritus: A Case Report (ASRA-FALL 2026) - Oct 27, 2026 - Pres time: Nov 5, 2026; 08:49 AM - 08:57 AM; Location: Tampa 1-2; "Materials and Methods : A total of 70 units (5 units per site) of Onabotulinumtoxin A (Botox) was injected subcutaneously over the following muscular surface landmarks, bilaterally, based on the subjective distribution of her symptoms: anterior deltoid (1 site), biceps brachii (3 sites), and brachioradialis (2 sites)...Despite dermatologic and rheumatologic workup, including topical capsaicin and lidocaine, as well as a trial of dupilumab, she reported minimal improvement of her symptoms, suggesting a neuropathic etiology of her symptoms. She was initiated on gabapentin, duloxetine, and a compounded topical cream (amitriptyline 3%, gabapentin 6%, lidocaine 5%), which provided some relief...Its neuronal, glial, and immune-modulating effects may reduce itch transmission. Subcutaneous botulinum toxin may be a treatment option for refractory neuropathic itch, although further studies are needed to define its efficacy, safety, and optimal dosing."
Case report • Clinical • Atopic Dermatitis • Dermatitis • Dermatology • Immunology • Musculoskeletal Diseases • Orthopedics • Pruritus
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