Resistance to CDK7 inhibitors directed by acquired mutation of a conserved residue in cancer cells.

samuraciclib (CT7001) - Carrick Therap

http://www.ncbi.nlm.nih.gov/pubmed/40921851

Basil J Greber; Charlotte L Bevan; Chun-Fui Lai; Ellen Olden; Laki Buluwela; R Charles Coombes; Simak Ali; Victoria I Cushing

Sep 9, 2025