Preclinical development and a case report of a nanobody-based CLDN18.2 CAR-T IMC002 with reduced on-target off-tumor toxicity.

CAR-T cells - Chinese PLA General Hospital

IMC002 - Immunofoco

http://www.ncbi.nlm.nih.gov/pubmed/41208285

Chao Li; Chuan-Hua Zhao; Jianming Xu; Juan Li; Jun Zhou; Lupeng Qiu; Minmin Sun; Qiaoyong Yi; Rong-Rui Liu; Ruidong Hao; Shuangshuang Zhang; Sicheng Du; Sisi Ye; Tianhang Luo; Yantao Li; Ying Zhang; Yuting Li

Nov 10, 2025