In the presence of pre-existing anti-AAV immunity, systemic administration of low dose AAV triggers complement activation within minutes

ADVM-053 - Adverum Biotech

https://pag.virtual-meeting.org/US/asgct2026/en-US/pag/presentation/684953

Anthony Caragiulo1; Jonathan B. Rosenberg1; Bishnu P. De1; Stephen M. Kaminsky1; Heather R. Martin1,2; Samuel Butler3; Jordi Rodó Morera3; Dolan Sondhi1; Ronald G. Crystal1

Mar 22, 2026