Identification of a selective FLT3 inhibitor with low activity against VEGFR, FGFR, PDGFR, c-KIT, and RET anti-targets.

Xospata (gilteritinib) - Astellas

Vanflyta (quizartinib) - Daiichi Sankyo

Iclusig (ponatinib) - Takeda, Otsuka, Incyte

Rydapt (midostaurin) - Novartis

crenolanib (ARO-002) - AROG

http://www.ncbi.nlm.nih.gov/pubmed/37971283

Allison L Kempen; Desmond Akwata; Herman O Sintim; Neetu Dayal; Nickolas R Brauer

Nov 17, 2023