The Troll Is Weakened but Not yet Defeated: An Update on Cytomegalovirus Management in Transplantation From the International CMV Symposium 2025. (PubMed, Transpl Infect Dis) - May 5, 2026 - "The Transplantation Society, European Conference on Infections in Leukaemia, and American Society for Transplantation and Cellular Therapy each released updated recommendations reflecting significant advances, including letermovir prophylaxis for hematopoietic stem cell and high-risk renal transplantation, maribavir for resistant or refractory disease, and cell-mediated immunity testing to guide personalized prevention strategies. The integration of solid organ and hematopoietic stem cell transplant expertise enabled cross-disciplinary learning while respecting population-specific differences. As the transplant community advances toward defeating the "troll of transplantation," continued therapeutic innovation must be coupled with implementation science, economic analyses, and global cooperation to ensure all transplant recipients benefit from these advances."
Journal • Bone Marrow Transplantation • Cognitive Disorders • Cytomegalovirus Infection • Hematological Malignancies • Infectious Disease • Leukemia • Nephrology • Oncology • Solid Organ Transplantation • Transplantation
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; Camille N Kotton; Julián Torre-Cisneros; Martina Sester
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