LOW-LEVEL PRETRANSPLANT CMV DNAEMIA IS ALREADY A RISK FACTOR FOR POSTTRANSPLANT CMV INFECTION AFTER ALLOGENEIC HEMATOPOIETIC CELL TRANSPLANTATION (EBMT 2026) - Mar 14, 2026 - Abstract #A258; Pres time: Mar 23, 2026; 06:00 PM - 07:00 PM; Location: VELAZQUEZ; "Background: Clinically-significant CMV infections (csCMVi) still occur in allogeneic hematopoietic cell transplant recipients (allo-HCTr), even on letermovir prophylaxis... Whereas pre-HCT CMV DNAemia was strongly associated with increased post-HCT csCMVi incidence, the magnitude of the VL is not associated with an increased risk. This suggests that any DT pre-HCT CMV DNAemia may represent an activity of CMV reservoir and could be considered as a relevant risk factor for csCMVi, regardless of the VL."
Clinical • Post-transplantation • Pre-transplantation • Acute Graft versus Host Disease • Bone Marrow Transplantation • Cytomegalovirus Infection • Graft versus Host Disease • Immunology • Infectious Disease • Transplantation
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Catia Vieira Gomes1; Manuel Schibler1; Laurent Kaiser1; Yves Chalandon1; Stavroula Masouridi-Levrat1; Christian Van Delden1; Dionysios Neofytos1; Lena Royston1
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