IMPACT OF DONOR CMV-SPECIFIC HUMORAL AND CELL-MEDIATED IMMUNITY ON CMV-IMMUNE RECONSTITUTION AND INFECTION AFTER ALLOGENEIC HEMATOPOIETIC STEM-CELL TRANSPLANTATION (EBMT 2026) - Mar 14, 2026 - Abstract #B108; Pres time: Mar 24, 2026; 06:00 PM - 07:00 PM; Location: VELAZQUEZ; "Most patients received PTCy-based GVHD prophylaxis (94%) and 53% received primary CMV-prophylaxis with letermovir (Recipients who were CMV IgG + and who deemed at high risk of CMV reactivation as per Spanish reimbursement policy)... Donor CMV-specific humoral and cellular immunity contribute to earlier CMV-CMI reconstitution after allo-HSCT, consequently reducing the risk of csCMV infection. This could have implications in graft viability and donor selection."
Bone Marrow Transplantation • Cytomegalovirus Infection • Graft versus Host Disease • Immunology • Infectious Disease • Transplantation • IFNG
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Guillermo Ramos Moreno1; Isabel Rodríguez Goncer1,2; Jose María Sánchez Pina1; Pilar Martínez1; Magdalena Corona de Lapuerta1; Adolfo Jesús Sáez Marín1; Daniel Gil Alós1; María Nieves López Muñoz1; María Luisa Palacios Berraquero1; Alberto Blanco Sánchez1; Mario Fernández Ruiz1,2; Asunción Pérez Jacoíste1; Jose María Aguado1,2; Joaquín Martínez López1,2; María Calbacho Robles1
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