MINI-ATG/TBI CONDITIONING REGIMEN FACILITATES CURE OF ACQUIRED APLASTIC ANEMIA IN CHILDREN VIA UNRELATED UMBILICAL CORD BLOOD TRANSPLANTATION (EBMT 2026) - Mar 14, 2026 - Abstract #B027; Pres time: Mar 24, 2026; 06:00 PM - 07:00 PM; Location: VELAZQUEZ; P4 | "In the mini-ATG/TBI group, odd-numbered patients received avatrombopag starting on day +7 to promote platelet engraftment, while even-numbered patients received thrombopoietin (TPO)...However, CMV viremia incidence differed significantly (6.25% vs. 66.67%, P=0.001), attributed to the widespread use of letermovir for CMV prophylaxis after 2024... These data support the mini-ATG/TBI regimen as an effective conditioning approach for UCBT in acquired aplastic anemia, demonstrating particular utility in pediatric patients or low body weight adults."
Clinical • Acute Graft versus Host Disease • Anemia • Aplastic Anemia • Epstein-Barr Virus Infections • Graft versus Host Disease • Hematological Disorders • Hemophagocytic lymphohistiocytosis • Immunology • Infectious Disease • Rare Diseases • Septic Shock • Transplantation • Transplantation Associated Thrombotic Microangiopathy
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Xia Chen1; Fang Liu1; Wenyu Yang1
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