Threshold for cytomegalovirus DNA PCR for preemptive treatment after allogeneic stem cell transplantation. (PubMed, Int J Hematol) - Feb 11, 2026 - "In low-risk patients, a threshold of 500-750 IU/mL balances avoiding spontaneous resolution and increasing delayed treatment. PCR thresholds of 50 and 150 IU/mL may be appropriate for initiating preemptive therapy in high-risk patients treated and not treated with letermovir, respectively, while 500-750 IU/mL may be optimal for low-risk patients."
Journal • Cytomegalovirus Infection • Graft versus Host Disease • Immunology • Infectious Disease • Transplantation
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Atsuto Noguchi; Ayumi Gomyo; Chihiro Yamamoto; Daisuke Minakata; Daizo Yokoyama; Hideki Nakasone; Hirotomo Nakashima; Junko Takeshita; Kaoru Hatano; Kazuki Hyodo; Kazuya Sato; Ken Ohmine; Kento Umino; Machiko Kusuda; Masahiro Ashizawa; Rui Murahashi; Ryutaro Tominaga; Shin-Ichiro Fujiwara; Shinichi Kako; Shuka Furuki; Shun-Ichi Kimura; Shunsuke Koyama; Shunto Kawamura; Yoshinobu Kanda; Yumiko Toda
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