Ganciclovir Pharmacokinetic Monitoring in a Pediatric Stem Cell Transplant Recipient with Human Cytomegalovirus Viremia: A Case Report (TCT-ASTCT-CIBMTR 2026) - Jan 8, 2026 - Abstract #894; 457; Pres time: Feb 5, 2026; 06:30 PM - 08:00 PM; Location: Hall AB (Salt Palace Convention Center); "He failed to clear CMV with standard valganciclovir and ganciclovir pediatric dosing; resistance testing was negative... After foscarnet discontinuation, ganciclovir was continued at home...Letermovir was subsequently prescribed for secondary prophylaxis... Inadequate ganciclovir exposure may lead to treatment failure or antiviral resistance. To our knowledge , this is the first reported case of AUC -guided ganciclovir dosing in a pediatric SCT patient with CMV viremia. AUC-guided dosing is a potentially safe and effective option for pediatric patients unable to clear CMV with traditional dosing strategies ."
Case report • Clinical • PK/PD data • Cytomegalovirus Infection • Gastroenterology • Gastrointestinal Disorder • Hematological Disorders • Hepatitis C • Hepatology • Immunology • Inflammation • Pediatrics • Pneumonia • Transplantation
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Carmen D Echols, PharmD, BCPPS, CPP 1; Mike Winstead, MD 2; Cammie Moore Presler, DNP, RN, CPNP, CPON 2; Zachary I Willis, MD, MPH 3; William Wilson, PharmD, BCIDP 1
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