Closed-loop integration of life cycle assessment in complex molecule synthesis: Case study antiviral Letermovir | Poster Board #1200 (ACS-Fall 2026) - Aug 24, 2026 - Abstract #4527150; Pres time: Aug 25, 2026; 01:00 PM - 03:00 PM; Location: Hall F2 - POSTERS (McCormick Place Convention Center); "Across both routes, key environmental contributions are traced to asymmetric catalysis and metal-mediated coupling steps, identifying critical leverage points for sustainability improvement. Overall, this work demonstrates how embedding LCA into synthetic design complements classical green chemistry metrics and supports informed, sustainability-driven decision-making in complex multistep synthesis."
Case study • Clinical
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Sander Folkerts; Erick Carreira; Javier Perez-Ramirez; Gonzalo Guillén-Gosálbez; Maximilian Hoepfner
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