Identification of a binding pocket of letermovir in the terminase subunit pUL56 of human cytomegalovirus. (PubMed, Sci Rep) - Mar 26, 2025 - "This results in a changed distribution of the Gibbs free binding energy. To circumvent the absolute resistance of C325 mutations a further modification of letermovir might solve the problem and leads to optimizing drug targeting capacity."
Journal • Cytomegalovirus Infection
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Elke Bogner; Hans Tietze; Lukas M Kmetsch
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