Preliminary embryo-fetal developmental toxicity study of pritelivir in CD1-IGS mice. (PubMed, Sci Rep) - Jun 22, 2026 - "Placenta-to-maternal plasma and fetus-to-maternal plasma concentration ratios in mice were 0.4 and 0.2, respectively, indicating transfer but not accumulation of pritelivir in the fetoplacental compartment. Taken together, our findings support further preclinical studies of pritelivir for its use in pregnancy."
Journal • Preclinical • Herpes Simplex
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Bandana Bera; Brendan Prideaux; Erik Rytting; Svetlana L Patrikeeva; Sydni C Zacharias; Tatiana N Nanovskaya; Valentina F Bryant; Xiaoming Wang
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