Cytomegalovirus DNA "Blips" After Conversion to Letermovir Secondary Prophylaxis in High-Risk Kidney Transplant Recipients (ATC 2026) - Jun 17, 2026 - Abstract #Abstract 127; Pres time: Jun 20, 2026; 04:42 PM - 04:54 PM; Location: 205BC' Level 2; "VL increases are common during LET SP and typically occur in the first 2 weeks after conversion. While viral replication typically trends down with ongoing LET, theoretically attributable to LET mechanism of action (ie "blips"), replication infrequently completely resolves to negativity during SP. Additionally, clinically significant replication that is attributable to prophylaxis failure can occur."
Clinical • Cytomegalovirus Infection • Transplantation
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M. Jorgenson 1; J. Descourouez 1; H. Kleiboeker 1; C. Saddler 2; S. Parajuli 2
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