Human cytomegalovirus terminase inhibitors letermovir, tomeglovir, and the halogenated benzimidazoles modify DNA cleavage/packaging to generate a super-genomic DNA species by cleavage site skipping.

Prevymis (letermovir) - Merck (MSD)

http://www.ncbi.nlm.nih.gov/pubmed/42167446

Ahmed Al Qaffas; Amine Ourahmane; Anne Sauer; Desy Balalimbong; Dirk P Dittmer; Jian Ben Wang; Justin Landis; Michael A McVoy; Razia Moorad; Stephen J Dollery

May 22, 2026