Target Attainment and Clinical and Biochemical Parameters Associated with the Pharmacokinetics of 12 Tyrosine Kinase Inhibitors. (PubMed, Clin Pharmacokinet) - Sep 5, 2026 - "Target attainment was suboptimal for most TKIs, supporting the need for TDM-guided optimisation and individualised dosing. Associations between TKI exposure and renal, hepatic, and haematological parameters further support personalised treatment strategies."
Journal • PK/PD data • Hematological Disorders • Oncology
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Anouk Dontje; Anthonie J van der Wekken; Bahez Gareb; Daan J Touw; Esther Broekman; Marjolijn N Lub-de Hooge; Paola Mian; Saskia K Klein; Thijs H Oude Munnink; Zaid N Al Shirity
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