Steroid-Refractory, Grade 3 Acute Gut GVHD Following Haploidentical Allogeneic HSCT for High-Risk AML (SOHO 2026) - Sep 1, 2026 - Abstract #AML-043; "Despite sequential treatment with high-dose corticosteroids, ruxolitinib, and extracorporeal photopheresis (ECP), the patient developed refractory diarrhea and cold sepsis. Vedolizumab was initiated as third-line therapy with gradual symptomatic improvement. This case highlights the complexities of managing SR GIGVHD in elderly transplant recipients and underscores the role of vedolizumab as an effective, gut-targeted therapeutic option."
Acute Myelogenous Leukemia • Hematological Malignancies • Leukemia • Oncology
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Manzoor Khan MBBS; Maria Losa Azucena MD; Sohail Ahmad MBBS
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