Jakafi (ruxolitinib) - Incyte
A Gut Feeling Gone Wrong: Duodenal Perforation in Post-PV Myelofibrosis on Ruxolitinib With Chronic Active Colitis (ACG 2026) - Aug 29, 2026 - Abstract #P2132; Pres time: Oct 11, 2026; 03:30 PM - 07:00 PM; Location: Exhibit Halls A - D (Level 3); "Erythematous mucosa in the appendiceal orifice (A), ascending colon (B), transverse colon (C), splenic flexure (D) and descending colon (E) with noted congested/friable mucosa (yellow arrow). Marked mucosal ulceration and bleeding (yellow arrow) in the distal rectum (F) Figure: Figure 2A-B: CT Abdomen and Pelvis without contrast showing new intra-abdominal free air concerning for pneumatosis involving a loop of small bowel (yellow arrows)." 
Cardiovascular • Crohn's disease • Fibrosis • Gastroenterology • Gastrointestinal Disorder • Hematological Disorders • Hepatology • Immunology • Inflammation • Myelofibrosis • Peptic Ulcer • Portal Hypertension • Thrombocytopenia
https://acg2026.eventscribe.net/ajaxcalls/PosterInfo.asp?efp=R01PT1FGR0UyNjkyNQ&PosterID=832853&rnd=0.2885369
 
Reshma John; MD; Aqsa Sorathia; MD; Mahmoud Khellah; MD; Noma Shri; MD; Ragul Manoharan; MD; Nizar Alyassin; MD; Dhruv Patel; DO; Kashyap Chauhan; MD; Walid Baddoura; MD; Yana Cavanagh; MD
 
Aug 29, 2026
 
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