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Opzelura (ruxolitinib cream) - Incyte
Efficacy and safety of JAK inhibitors for vitiligo: an updated systematic review and meta-analysis of randomized controlled trials. (PubMed, J Dermatolog Treat) - Aug 29, 2026 - "For F-VASI50, they were superior to tacrolimus (RR 1.88, 95% CI 1.02-3.45) but not significantly different from dexamethasone (RR 2.17, 95% CI 0.95-4.94). JAK inhibitors are effective and well tolerated for vitiligo. Topical ruxolitinib is supported as a first-line option for limited facial disease; oral agents show promise but require longer-term safety data." 
Clinical • Journal • Retrospective data • Review • Dermatology • Immunology • Vitiligo
http://www.ncbi.nlm.nih.gov/pubmed/42664062
 
Changxia Xiong; Chunxiao Bai; Guangshan Chen; Jingpeng Chen; Xingwu Duan; Yi Chen; Yongxiang Long; Ziyi Lin
 
Aug 29, 2026
 
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