Targeting SLC7A11 sensitizes colorectal cancer cells to elesclomol-Cu-induced cuproptosis via the GSH-GPX4 axis.

erastin - Whitehead Institute for Biomedical Research, Dana-Farber Cancer Institute, Columbia University, Prolexys

elesclomol (STA-4783) - Madrigal Pharma

http://www.ncbi.nlm.nih.gov/pubmed/41519053

Fangzhou Ye; Huanqing Li; Jiayi Wang; Jun Jiang; Li Feng; Songhua Bei; Xiaohong Zhang

Jan 11, 2026