SLC7A11 upregulation via AR and NEDD4L ubiquitination contributes to ferroptosis inhibition and enzalutamide resistance in castration-resistant prostate cancer.

Xtandi (enzalutamide) - Pfizer, Astellas

erastin - Whitehead Institute for Biomedical Research, Dana-Farber Cancer Institute, Columbia University, Prolexys

http://www.ncbi.nlm.nih.gov/pubmed/40764425

Bao Wang; Bianjiang Liu; Chesong Zhao; Hengtao Bu; Jie Li; Luotong Xue; Min Tang; Pu Li; Shuaimei Liu; Xiaoxin Meng; Xiyuan Chen; Yurong Zhang; Zhixin Jiang

Aug 6, 2025