The mechanism of lncRNA SSTR5-AS1 promoting ferroptosis resistance and immune escape in ovarian cancer cells by recruiting STAT3 to regulate SLC7A11 expression.

erastin - Whitehead Institute for Biomedical Research, Dana-Farber Cancer Institute, Columbia University, Prolexys

The mechanism of lncRNA SSTR5-AS1 promoting ferroptosis resistance and immune escape in ovarian cancer cells by recruiting STAT3 to regulate SLC7A11 expression. (PubMed, Cancer Genet) - Jul 29, 2025 - "SSTR5-AS1 promoted SLC7A11 transcription and expression by recruiting STAT3, thereby promoting ferroptosis resistance and immune escape of OC cells."
Journal • Gynecologic Cancers • Oncology • Ovarian Cancer • Solid Tumor • CD8 • SLC7A11 • SSTR5 • SSTR5-AS1 • STAT3

http://www.ncbi.nlm.nih.gov/pubmed/40716132

Chun Li; Huimin Wang; Qiong Wei; Yi Yang; Yuping Li

Jul 29, 2025