Herbacetin Alleviates Ferroptosis via Hif-1α/SLC7A11/GPX4 Axis in Traumatic Brain Injury. (PubMed, Free Radic Biol Med) - Jun 24, 2025 - "In our study, we employed an erastin and RSL3-induced ferroptosis model using HT22 and PC12 cells. RNA-seq analysis and Hif-1α knockdown experiments in HT22 cells supported this conclusion. In conclusion, our findings provide a potential therapeutic basis for the clinical use of HBT in preventing neuronal ferroptosis following TBI."
Journal • CNS Disorders • Vascular Neurology • GPX4 • HIF1A • SLC7A11
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Dongchen Xu; Fucai Long; Hao Wang; Haoqi Ni; Jiawei Chen; Liuqing Gu; Peng Zhang; Qichuan Zhuge; Wenqi Qian; Xiangxiang Lin; Xijun Chen
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