Stress-induced sympathetic stimulation inhibits sorafenib-induced ferroptosis in renal cell carcinoma (AACR 2025) - Mar 26, 2025 - Abstract #5558; Pres time: Apr 29, 2025; 02:00 PM - 05:00 PM; Location: Section 18; Poster Board No: 20; "Isoproterenol (ISO), a non-specific β-adrenergic receptor agonist, was added into RCC cell lines ACHN and A498 before the addition of clinically-used-drugs (sorafenib, cabozantinib, lenvatinib, and rapamycin), and cell viability was analyzed by MTS assay... Stress-induced sympathetic stimulation inhibits sorafenib-induced ferroptosis in RCC."
Genito-urinary Cancer • Oncology • Renal Cell Carcinoma • Solid Tumor • ADRB2
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Masaki Ushijima; Sei Naito; Hiromi Ito; Osamu Ichiyanagi; Takafumi Narisawa; Norihiko Tsuchiya
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