Glutathione peroxidase 4 (GPX4) and obesity interact to impact tumor progression and treatment response in triple negative breast cancer. (PubMed, Cancer Metab) - Feb 26, 2025 - "GPX4 suppression, alone or with current TNBC therapies, impacts outcomes in preclinical TNBC models with or without obesity and offers a new, plausible mechanistic target for TNBC treatment."
IO biomarker • Journal • Breast Cancer • Genetic Disorders • Obesity • Oncology • Solid Tumor • Transplantation • Triple Negative Breast Cancer • GPX4
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Alyssa N Ho; Bennett H Brosnan; Dorothy Teegarden; Elaine M Glenny; Emily N Devericks; Hannah M Malian; Michael F Coleman; Michael K Wendt; Stephen D Hursting
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