METTL3-mediated m6A modification of SLC7A11 enhances nasopharyngeal carcinoma radioresistance by inhibiting ferroptosis. (PubMed, Int J Biol Sci) - Feb 24, 2025 - "Furthermore, silencing SLC7A11 or employing the ferroptosis inducer Erastin negated the promoting effect of METTL3 on NPC cell radioresistance. These findings suggest that METTL3 could be a novel therapeutic target for overcoming radiotherapy resistance in NPC."
Journal • Nasopharyngeal Carcinoma • Oncology • Solid Tumor • METTL3 • SLC7A11
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Baisheng Lin; Feixiang Wang; Guofeng Xie; Jian Zhang; Kai Liao; Li Wang; Maohua Qin; Yunen Lin; Zili Dai
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