erastin - Whitehead Institute for Biomedical Research, Dana-Farber Cancer Institute, Columbia University, Prolexys
MiR-224-3p regulates ferroptosis and inflammation in lens epithelial cells by targeting ACSL4. (PubMed, Exp Eye Res) - Feb 23, 2025 - "Also, miR-224-3p effectively inhibited ferroptosis induced by erastin and decreased the level of expression of IL-6. Ferroptosis and inflammation occur in the eyes of HMC patients. Additionally, miR-224-3p increases the viability of HLECs by regulating ferroptosis and inflammation via ACSL4 targeting." 
Journal • Cataract • Inflammation • Ophthalmology • ACSL4 • GPX4 • IL6 • MIR224 • TNFA
http://www.ncbi.nlm.nih.gov/pubmed/39986367
 
Che Xu; Feng Sun; Jianfeng Wang; Juan Li; Mengyue Xu; Na Li; Yan Liu; Yuanyuan Han
 
Feb 23, 2025
 
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