Very early onset inflammatory bowel disease in Jordan: a single-center case series of clinical, genetic, and therapeutic features. (PubMed, BMC Pediatr) - Oct 24, 2026 - "VEOIBD in Jordan is characterized by early presentation, genetic heterogeneity including co-occurring variants of uncertain significance, and poor response to conventional therapy. Limited access to targeted agents and HSCT significantly impacts outcomes. Early genomic testing, multidisciplinary management, and improved therapeutic access are essential for better prognosis."
Journal • Retrospective data • Bone Marrow Transplantation • Gastroenterology • Gastrointestinal Disorder • Gene Therapies • Immunology • Infectious Disease • Inflammation • Inflammatory Bowel Disease • Pediatrics • Transplantation • GUCY2C • RIPK1
|
|
Ayah Alsmadi; Eyad Altamimi; Hala Almomani; Maria Shurman; Nicole Issi
|