Resistance-centered pharmacology of DNA damage response-targeted therapy: Mechanisms, predictive biomarkers, and biomarker-guided adaptive treatment strategies in solid tumors.

peposertib (M3814) - EMD Serono

ART6043 - Artios Pharma

ceralasertib (AZD6738) - AstraZeneca

saruparib (AZD5305) - AstraZeneca

alnodesertib (ART0380) - Artios Pharma

http://www.ncbi.nlm.nih.gov/pubmed/42314345

Fei Zhao; Gayoung Seo; Jeongmin An; Sisi Qin; Tang Siyao; Wang Qiao; Wootae Kim; Xu Zhichao

Jun 19, 2026