Structural and Computational Analyses of the Unique Interactions of Opicapone in the Binding Pocket of Catechol O-Methyltransferase: A Crystallographic Study and Fragment Molecular Orbital Analyses.

Ongentys (opicapone) - Ono Pharma, Neurocrine, BIAL

Comtan (entacapone) - Novartis, Orion Corp

tolcapone - Generic mfg.

http://www.ncbi.nlm.nih.gov/pubmed/37436881

Hiroshi Iijima; Kaori Fukuzawa; Katsuki Takebe; Mamoru Suzuki; Narikazu Uzawa; Satoko Shirai; Takao Kuwada-Kusunose; Tomoko Takamiya

Jul 12, 2023