Efficacy of MAO-B and COMT inhibitors on quality of life in patients with Parkinson&#39;s disease: a Bayesian network meta-analysis.

Xadago (safinamide) - Meiji Seika, Zambon, Supernus Pharma

selegiline - Generic mfg.

Ongentys (opicapone) - Ono Pharmaceutical, Neurocrine Biosciences, BIAL

Comtan (entacapone) - Novartis, Orion Corp

tolcapone - Generic mfg.

http://www.ncbi.nlm.nih.gov/pubmed/41716552

Kyum-Yil Kwon; Seon-Min Lee; Sung Ryul Shim; Taeho Greg Rhee; Yu Jin Jung

Feb 20, 2026