Selection of affinity-enhanced T-cell receptors for adoptive T-cell therapy targeting MAGE-A10 (AACR 2018) - Mar 16, 2018 - Abstract #2564 / 23; Pres time: Apr 16, 2018; 01:00 PM - 05:00 PM; Location: Section 24; P1; "The X-scan method permitted us to select the most
specific and potent candidate for further pre-clinical
testing. This MAGE-A10TCR is now being studied in clinical
trials to treat HLA-A2+ patients with non-small cell lung
cancer, urothelial cancers, melanoma, or head and neck
cancers."
Bladder Cancer • Genito-urinary Cancer • Head and Neck Cancer • Lung Cancer • Melanoma • Non Small Cell Lung Cancer • Oncology • Solid Tumor • Urothelial Cancer
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Ellen Border1, Joseph P. Sanderson1, Thomas Weissensteiner1, Natalie Hyland1, Tom Holdich1, Francine Brophy2, Rafael Amado2, Andrew Gerry1, Nicholas Pumphrey1. 1Adaptimmune, Oxford, United Kingdom; 2Adaptimmune, Philadelphia, PA
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