Progesterone Receptor Expression Is More Prognostic Than Estrogen Receptor and Ki-67 Expression in Invasive Lobular Carcinoma Compared to Invasive Ductal Carcinoma: A Multi-Institutional Study (USCAP 2017) - Mar 7, 2017 - Abstract #191; Pres time: Mar 8, 2017; 01:00 PM; Location: Exhibit Hall 1; "...We examined the relationship between the Oncotype DX recurrence score (ODXRS), estrogen receptor (ER), PR and Ki-67 in ILC and IDC... We found no significant difference (see Table) in the ODXRS (p=0.09) or the modified ER H-score (mERH, p=0.87) between ILC and IDC. We found a significant difference in the modified PR H-score (mPRH, p=0.009) and Ki-67 (p < 0.001) between ILC and IDC. ILC and IDC had a significantly stronger correlation (p < 0.05) between the mPRH and ODXRS (R2= 0.18 [ILC]; R2= 0.24 [IDC]) compared to the correlation between the mERH and ODXRS (R2= 0.03 [ILC]; R2= 0.12 [IDC]), with ILC having the stronger difference in correlation."
Biomarker • Clinical • Biosimilar • Breast Cancer • Hormone Receptor Breast Cancer • Oncology
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Roula Katerji, Mary Ann Sanders, Ping Tang, David Hicks, Bradley M Turner. University of Rochester Medical Center, Rochester, NY; University of Louisville, Louisville, KY
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