Imidazolyl ethanamide pentandioic acid promotes hematopoietic recovery following sublethal radiation in a murine model. (PubMed, Int J Radiat Biol) - May 27, 2025 - "Our results reveal that IEPA attenuated radiation-induced DNA damage and improved recovery of HSCs/HPCs, myeloid as well as lymphoid progenitors, accompanied by increases in platelets in blood, megakaryocytes in BM and splenic CD34+ cells. IEPA shows promise as a radiation mitigator, with no significant benefit observed from adding GM-CSF."
Journal • Preclinical • Hematological Disorders • Infectious Disease • CD34 • CSF2 • FOXM1 • H2AX
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Basveshwar Gawali; Corinna Asang; Dirk Pleimes; Maciej T Czajkowski; Nikita Singh; Seren Sevim-Wunderlich; Snehalata A Pawar; Srishti Munjal Mehta; Suresh Veeraperumal
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