A Practical Alternative to Refine the Estimate of fmCYP3A4 and Evaluate Drug-Drug Interaction Potential for Ziftomenib Using PBPK Modeling to Inform Labeling.

Komzifti (ziftomenib) - Kura Oncology, Kyowa Kirin

Cresemba (isavuconazonium sulfate) - Astellas, Basilea

rifampicin - Generic mfg.

midazolam hydrochloride - Generic mfg.

itraconazole - Generic mfg.

http://www.ncbi.nlm.nih.gov/pubmed/42682186

Amitava Mitra; Chara Litou; Hannah M Jones; Ian E Templeton; Julie Mackey Ahsan; Marilyn Tabachri; Mollie Leoni

Sep 3, 2026