Padcev (enfortumab vedotin-ejfv) - Astellas, Pfizer
Body Mass Index-Related Trends in Adverse Events with Enfortumab Vedotin: Analysis of a Pharmacovigilance Database and Medical Records. (PubMed, Biol Pharm Bull) - Sep 7, 2026 - "A high BMI was associated with an increased risk of certain EV-related skin toxicities, potentially exacerbated by dosing based on actual versus IBW, whereas a low BMI may increase susceptibility to infections such as pyelonephritis. Individualizing risk assessment and dosing based on patient physique may improve the safety and efficacy of EV therapy." 
Adverse events • Journal • Retrospective data • Dermatology • Infectious Disease • Nephrology • Oncology • Pruritus • Solid Tumor • Steven-Johnson Syndrome • Urothelial Cancer
http://www.ncbi.nlm.nih.gov/pubmed/42702557
 
Motoki Kei; Ryosuke Yamaga; Satoko Karaki; Shiori Sato; Toshimasa Ito; Yoshihiro Uesawa
 
Sep 7, 2026
 
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