Trulance (plecanatide) - Bausch Health
Linzess (linaclotide) - Ironwood Pharma, AbbVie
Zelnorm (tegaserod) - Novartis
Amitiza (lubiprostone) - Takeda, Mallinckrodt
Ibsrela (tenapanor) - Ardelyx
Patients' Real-World Experiences With Pharmacologic Therapies for Irritable Bowel Syndrome With Constipation: A Mixed-Methods Analysis and Classification of Social Media and E-Forum Posts. (PubMed, Neurogastroenterol Motil) - Sep 5, 2026 - "Social media provides unique insights into IBS-C patients' real-world experiences with FDA-approved therapies. Findings highlight variability in efficacy, biopsychosocial impacts, and adherence challenges, underscoring the need for shared decision making and proactive management of barriers to optimize outcomes." 
Journal • Real-world evidence • CNS Disorders • Constipation • Gastroenterology • Gastrointestinal Disorder • Mood Disorders • Psychiatry
http://www.ncbi.nlm.nih.gov/pubmed/42694017
 
Allistair Clark; Brennan M R Spiegel; Carine Khalil; Christopher V Almario; David P Rosenbaum; Graciela Gonzalez-Hernandez; Ivan Flores Amaro; Jordy O'Campo; Karen O'Connor; Karisma K Suchak; Sharon Funk; Zoe Krut
 
Sep 5, 2026
 
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